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Improving solid dosage understanding & performance

Optimized for non-destructively determining heterogeneity and integrity of pharmaceutical cores and coatings, the TeraView TPI imaga 2000 can be used as a routine part of your product and process development to:

  • Enable rational product design and control
  • Build ICH compliant product registration
  • Mitigate risk of product failure
  • Optimize manufacturing costs


TeraView provides the expertise to investigate and assess critical attributes that impact the product performance such as:

  • Density variation in tablet cores
  • Crack propagation leading to tablet failure such as capping and de-lamination
  • Coating thickness, density, integrity and uniformity
  • Core – coat interaction to establish impact of coating process on the tablet core
  • Interaction between multiple coatings or core layers


Using chemometric software, TeraView can generate predictive models to support you through product and process development, and optimisation as well as defining the correct manufacturing space for successful scale-up and process transfer.

Tablet integrity   Using terahertz 3D imaging to determine integrity of tablet core and coating
   

 

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